May 3, 2024

News and Political Commentary

Bryan Johnson is being used as a human guinea pig in unproven tests to reprogram human genes in an island off Honduras

2 min read

With an estimated net worth of around $400 million, tech entrepreneur Bryan Johnson has access to the world’s best health care. But swapping blood with his 17-year-old son and 70-year-old father and undergoing daily body scans by a team of 30 doctors isn’t quite cutting it for the 46-year-old centi-millionaire who wants to be 18 again.

Now, the Blueprint founder is taking trips to the remote Caribbean island of Roatán to be injected with a genetically enhancing drug that’s not been approved by the FDA—and according to at least one scientist “will kill someone”.

At $25,000 a go, the gene therapy works by turbocharging the body’s production of follistatin—a protein that helps manage the production of other proteins and hormones—to reduce inflammation, increase muscle mass, and improve bone density. It is, according to Minicircle Inc, the small U.S. startup behind the therapy, one of humanity’s best hopes for “extreme longevity”.

The company opted not to charge Johnson for the follistatin therapy—but apparently, their treatment is a bargain.

“Most gene therapies cost more than $1 million a pop,” Walter Patterson, Minicircle’s co-founder and chief scientific officer, told Bloomberg. “This therapy is made so that anyone in the world can have access to it.”

Minicircle has yet to publish clinical trial data for its follistatin therapy, which is the first in a series of products Minicircle plans to roll out. It’s why scientists are issuing stark warnings about the dangers of trying out unregulated gene therapies.

“These have no evidence for working, don’t make sense from a scientific perspective and likely will kill someone by inducing cancer or liver failure,” Christin Glorioso, a physician and neuroscientist, wrote about follistatin and other unregulated gene therapies in her longevity and health newsletter.

A former FDA official helped Johnson weigh up the risks

For Minicircle, the benefit of…

Orianna Rosa Royle

2023-12-21 07:19:34

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